Safener Interactions with the Herbicide Target Site

Safener Interactions with the Herbicide Target Site 

These findings were in contrast to a report of competitive binding of the triti-ated dichloroacetamide safener R-29148 and the herbicides EPTC or alachlor at a proteinaceous component of maize seedling extracts. In addition, a good correlation was observed between competitive inhibition of [ H] R-29148 binding by other dichloroacetamide compounds and their effectiveness as safeners. This was taken as support for the hypothesis that dichloroacetamide safeners act as receptor antagonists for the herbicides EPTC and alachlor [24], 

---