Dichloroacetamide safener

Note - Acetochlor can be safened by several dichloroacetamide safeners other than dichlormid and furilazole. For example, the product Acenit contains the safener AD67 (MON4660) which has no assigned common name (see Table 5.1 for chemical structure). 

These findings were in contrast to a report of competitive binding of the triti-ated dichloroacetamide safener R-29148 and the herbicides EPTC or alachlor at a proteinaceous component of maize seedling extracts. In addition, a good correlation was observed between competitive inhibition of [ H] R-29148 binding by other dichloroacetamide compounds and their effectiveness as safeners. This was taken as support for the hypothesis that dichloroacetamide safeners act as receptor antagonists for the herbicides EPTC and alachlor [24],... 

The tolerance of maize to chlorsulfuron can be greatly increased by seed dressing with 1,8-naphthalic anhydride (NA) at 0.5%. Seed dressing with R 25788 (N,N-diallyl-2,2-dichloroacetamide) is less effective. NA has a safening effect on sorghum, rice at 5 g chlorsulfuron/ha. Wheat and barley are also well protected by NA to doses in excess of 100 g/ha active ingredient. 

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