Sadee

L. Johnson and W. Sade, Proceedings of the 18th Waterborne, Higher Solids, Powder Coating Symposium, pp. 65—77. 

This rather speculative figure is in reasonable agreement with Sadee et al. s (1976/1977) estimate. 

Identify potential blast sources. Data provided by the literature (Sadee et al. 1976/ 1977 Gugan 1978 Robert and Pritchard 1982) identified potential blast sources. The plot plan in Figure 7.4 shows that the cloud covered a substantial area the oxidation and caprolactam plants (indicated in Figure 7.4 as Section 7 and 27) and also the more-or-less open area toward the hydrogen plant. 

In each case, two different methods were used in arriving at estimates the HSE TNT-equivalency method and the multienergy method. The results, in the form of side-on blast peak overpressures for various distances from blast centers, are listed in Table 7.10. In addition, some peak overpressures estimated by Sadee et al. (1976/ 1977) from Flixborough-incident damage patterns are included. The photographs in Figures 7.6a and 7.6b illustrate the practical effects of such overpressures. 

Blast overpressures calculated by the TNT-equivalency method are in reasonable agreement with the overpressures deduced from observed damage (Sadee et al. 1976/1977). This is to be expected, because the Flixborough incident is one of the major vapor cloud explosion incidents on which the TNT-equivalency value of... 

Figure 7.6. (a) Damage to canteen building 130 m from explosion center. Estimated peak overpressure level 0.45-0.55 bar (Sadee et al. 1976/1977). (b) Damage to row of houses 535 m from explosion center. Estimated peak overpressure level 0.10-0.12 bar (Sadee et al. 1976/1977). 

Yan, Q. and W. Sadee. Human membrane transporter database a Web-accessible relational database for drug transport studies and pharma-cogenomics. AAPS PharmSci. 2000, 2, E20. 

Covitz, K. M., G. L. Amidon, and W. Sadee. Human dipeptide transporter, hPEPTl, stably transfected into Chinese hamster ovary cells. Pharm. Res. 1996, 13, 1631-1634. 

Targets. Amidon, X., Sadee, X. (eds), Kluwer Academic Publishers, New York, 1999, pp. 387-439. 

Anderle P, Rakhmanova V, Woodford K, Zerangue N, Sadee W (2003) Messenger RNA expression of transporter and ion channel genes in undifferentiated and differentiated Caco-2 cells compared to human intestines. Pharm Res 20 3-15. 

Anderle P, Huang Y, Sadee W (2004) Intestinal membrane transport of drugs and nutrients Genomics of membrane transporters using expression microarrays. Eur J Pharm Sci 21 17-24. 

Bahadduri PM, D Souza VM, Pinsonneault JK, Sadee W, Bao S, Knoell DL, Swaan PW (2005) Functional characterization of the peptide transporter PEPT2 in primary cultures of human upper airway epithelium. Am J Respir Cell Mol Biol 32(4)319-325. 

Sadee, W., Hoeg, E., Lucas, J., and Wang, D. X. (2001) Genetic variations in human G protein-coupled receptors implications for drug therapy. AAPS Pharmsci. 3. 

Tsuga, H., Kameyama, K., Haga, T., Honma, T., Lameh, J., and Sadee, W. (1998) Internalization and down-regulation of human muscarinic acetylcholine receptor m2 subtypes. Role of third intracellular m2 loop and G protein- coupled receptor kinase 2. J. Biol. Chem. 273, 5323-5330. 

Sade LE, Kanzaki H, Severyn D, Dohi K, Gorcsan J, III. Quantification of radial mechanical dyssynchrony in patients with left bundle branch block and idiopathic dilated cardiomyopathy without conduction delay by tissue displacement imaging. Am. J. Cardiol. 2004 94 514-8. 

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