Saccharomyces cerevisiae mutant screening

Sec7 Domain. The SECT protein was identified in a genetic screen of Saccharomyces cerevisiae mutants for defects in protein secretion (Achstetter et al., 1988). Structurally similar domains that were later recognized in other proteins involved in vesicular trafficking were referred as See domains and subsequently shown to be responsible for ARF activation (Morinaga et al., 1996 Peyroche et al., 1996) as well as its sensitivity to... 

Saccharomyces cerevisiae played an important role in the genetic analysis of riboflavin biosynthesis. Mating analysis between riboflavin auxotrophic mutants obtained by random mutagenesis and screening of haploid... 

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