S-Butyl mercaptan

Mercaptobutane. See s-Butyl mercaptan Mercaptobutanedioic acid. See Thiomalic acid Mercaptocyclopentane. See Cyclopentanethiol 1-mercaptodecane. See 1-Decanethiol Mercaptodiacetic acid. See Thiodiglycolic acid Mercapto diacetic acid, ethylene ester. See... 

Methyl-1-propanethiol 208-165-2 s-Butyl mercaptan 208-167-3 Barium carbonate 208-174-1... 

Sauers, R. R., Van Arnum, S. D. A Thio-Staudinger Reaction Thermolysis of a Vinyl Azide in the Presence of t-Butyl Mercaptan. Phosphorus, Sulfur Silicon Relat. Elem. 2003, 178, 2169-2181. 

DEE is readily absorbed through the skin. It is metabolized to -butyl mercaptan in the gastrointestinal tract by hydrolysis. The metabolite is excreted in the urine. A urinary metabolic profiling following oral administration of DEF to a lactating goat revealed that DEF is efficiently metabolized to many metabolites. The amount of DEF in liver, kidney, and muscle represented <1% of the total residue. A major metabolite, 3-hydroxybutylmethyl sulfone was found in the tissue, milk, and urine. The hydrolytic products of DEF, S,S-dibutyl phosphorodithioate and S-butyl phosphorothiate were identified as minor components in urine, comprising 5% and 4% of the total residue, respectively. 

S-Nucleophiles, like n-butyl mercaptan, react with nucleoside 2-thio-1,3,2-oxathiaphospholane monomers like 13, yielding nucleoside S-n-butyl-phospho-rodithioates (67) [93] (Scheme 17). 

Concurrent with the above research, we were considering reaction conditions for racemization. An initial test experiment based on Prof. Drueckhammer s conditions [26] convinced us that the search for acceptable racemizing conditions would not be arduous. A chiral thioester was prepared from (R)-l with thionyl chloride followed by 2-butyl mercaptan (94% yield). When this was mixed with toluene, l,8-diazabicyclo[5.4.0]undec-l-ene and Triton X-100 in phosphate buffer at pH 9.2, the heterogeneous mixture racemized completely in only 25 min. While the substrate had also degraded, such rapid racemization convinced us that we would be able to discover optimized conditions in a reasonable time period. 

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