Ru Catalyzed Asymmetric Hydrogenation of Quinolines

Subsequently, some commercially available chiral bidentate phosphine ligands 

Chiral Amine Synthesis Methods, Developments and Applications. Edited by Thomas C. Nugent Copyright 2010 WILEY-VCH Verlag GmbH Co. KGaA, Weinheim ISBN 978-3-527-32509-2 

Having established the optimal condition, the scope ofthe Ir catalyzed asymmetric hydrogenation of quinoline derivatives was explored. A variety of 2 substituted and 

Zhou and coworkers also studied the asymmetric hydrogenation of 2 functiona 

0mol% of catalysts prepared in situ from [Ir(COD)Cl]2 and 2.2 equiv of chiral 

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