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Simvastatin 4- Roxithromycin

Clinically important, potentially hazardous interactions with atorvastatin, bexarotene, cyclosporine, dicumarol, ezetimibe, fluvastatin, interferon alfa, lovastatin, nicotinic acid, pioglitazone, pravastatin, repaglinide, rosuvastatin, roxithromycin, simvastatin, statins, warfarin... [Pg.260]

Myopathy occurred in a 73-year-old woman taking simvastatin 80 mg/day and gemfibrozil 600 mg bd 4 days after she started to take roxithromycin 300 mg/day (18). [Pg.3084]

Cases of acnte rhabdomyolysis have been reported between lovas-tatin and azithromycin, clarithromycin, or erythromycin and between simvastatin and clarithromycin or roxithromycin. Macrolide antibacterials have also been potentially implicated in cases of rhabdomyolysis with atorvastatin and pravastatin. Pharmacokinetic stndies sn est that the macrolides increase the levels of the statins metabolised by CYP3A4 (namely atorvastatin, Iovastatin and simvastatin). [Pg.1104]


See other pages where Simvastatin 4- Roxithromycin is mentioned: [Pg.597]    [Pg.619]    [Pg.493]    [Pg.496]    [Pg.499]    [Pg.1105]    [Pg.36]    [Pg.325]   
See also in sourсe #XX -- [ Pg.1104 ]




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