Rotational dynamics accessible range

Solid-state NMR is, among techniques which measure molecular motion, capable of measuring an extremely wide range of motional rates. When Tj measurements are included, rate constants of more than 10 orders of magnitude are accessible. In addition to methyl group rotation, the combination of deuteration and solid-state NMR has yielded molecular dynamic information on phenyl groups, aliphatic chains, and ethene bound to transition metal centers. 

The future perspectives of this research area depend heavily on the application of CP-FTMW spectrometers, which have changed the scope of rotational spectroscopy in recent years. Chirped-pulse Fourier-transform microwave spectroscopy, combined with laser ablation, opens a new era in the investigation of isolated biomolecules, as can be shown by its application to carbohydrates as discussed in this chapter. The broad frequency and large dynamic range make it possible to extend the range of detectable conformers to less stable forms and to access structural determinations in molecular systems of increasingly larger sizes from measurements of heavy atom ( C, 0) isotopes detected in natural abun-... 

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