Rosacea sulfur

Leyden JJ, Grove G, Zerweck C (2004) A doubleblind, comparative facial tolerance study of a new 10% sodium sulfacetamide 5% sulfur aqueous gel (in a 10% urea vehicle) vs a 10% sodium sulfacetamide 5% sulfur topical suspension in rosacea acne subjects with sensitive skin. In Abstract of the 62nd Annual Meeting of the American Academy of Dermatology. Washington DC, February 6-11,2004. Abstract P66... 

Topical sulfacetamide is available alone as a 10% lotion (Klaron) and as a 10% wash (Ovace), and in several preparations in combination with sulfur for the treatment of acnevulgaris and acne rosacea. The mechanism of action is thought to be inhibition of P acnes by competitive inhibition of p-aminobenzoic acid utilization. Approximately 4% of topically applied sulfacetamide is absorbed percutaneously, and its use is therefore contraindicated in patients having a known hypersensitivity to sulfonamides. 

Blom I, Hommark AM (1984) Topical treatment with sulfur 10 per cent for rosacea. Acta Derm Venereol 64 358-359... 

Sauder DN, MiUer R, Gratto D, Danby W, Griffiths C, Phillips SB (1997) The treatment of rosacea the safety and efficacy of sodium sulfacetamide 10% and sulfur 5% lotion (Novacet) is demonstrated in a double-blind study. J Dermatol Treat 8 79-85... 

---