Root mean square radius analysis

In spite of all the recent success which can be traced to the three techniques, SANS, SAXS, SALS, there are serious limitations in their scope Q). For instance only average values, such as root-mean-square end-to-end distance and radius of gyration of a polymer chain can be extracted from these techniques. In other words, these techniques cannot provide information on the actual conformation or dimension of the individual polymer chain. Also since all three techniques are indirect, the analysis of the raw data is not straightforward and requires various manipulations and faith in existing theories to draw conclusions. Finally with regard to SANS, it must be noted that only a limited number of facilities in the U.S.have this capability, thus restricting its use. 

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