Role of PLD in Growth and Differentiation

PLD plays important roles in the response to wounding and other stresses through mediating the actions and production of stress hormones [140]. PLDa is specifically involved in the actions of abscisic acid and ethylene in plant senescence and in the control of water loss [140, 141]. Different stresses in plants lead to different expression patterns for PLD isozymes. 

In mammalian systems, PLD has been suggested to play roles in growth and differentiation, secretion, vesicle trafficking and transport, cytoskeletal rearrangements, superoxide production in phagocytes, protein translation and the production of lysophosphatidic acid (LPA). 

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