Role of Inflammation in Parkinsons Disease

Among the range of reactive species produced by glial cells, significant attention has been given to RNS due to the 

PD is a common neurodegenerative disorder characterized by motor abnormalities and a loss of primarily but not exclusively dopaminergic neurons. Other neuropathological hallmarks of PD include the proteinaceous inclusion, Lewy body and various inflammatory changes. The inflammation is made up of resident innate and to lesser extent adaptive immune cells. Similar inflammatory changes are found in both sporadic and familial non-PD parkinsonian syndromes and in experimental models 

What is the difference between parkinsonian syndrome and Parkinson s disease  

What are the similarities and differences in the inflammatory response among PD, the various parkinsonian syndromes, and the common experimental models of PD  

What are the arguments in favor of inflammation being a primary or a secondary event in PD  

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