Robotic sample changer

Optional) Robotic sample changer to facilitate exchange of samples for diffraction analysis (reeNote 8). 

Various optional peripherals may also be added to the instrument, such as variable temperature units that allow sample temperature regulation within the probe, robotic sample changers and so on. The coupling of NMR with other analytical techniques such as HPLC has become an established method through the development of flow probes and gained popularity in certain areas. The need for this will obviously depend on the type of samples handled and the nature of the experiments employed. 

Indeed, P NMR is widely used in a quantitative fashion. Computer-controlled and automated instruments, used in combination with robotic sample changers, make the large number of analytical samples much more manageable. With customized software, the spectrometer can automatically accumulate and store data, perform the Fourier transform and integration, calculate the relative distribution of species present and generate the analytical report. As an example, Figure 5 shows the output from a routine oligophosphate assay. 

The relatively high sensitivity and computing facilities associated with modem FT instruments have led to the development of fully automated systems with robotic sample changers. This ena-... 

The automation of sample preparation is clearly a requirement if one wants to measure a reasonably high number of test compounds. While sample changers have been used for a long time in analytical NMR laboratories, sample preparation robots have been introduced only recently, especially in the field of biomolecular NMR. They offer the great advantage that the samples are freshly prepared under identical conditions and delivered to the NMR instrument in a just-in-time fashion. Thus, they circumvent the disadvan-... 

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