Robotic dispensing advances

Source plates may be prepared in advance and stored frozen, depending upon fhe probe ink stability. In any case, source plates should be brought to ambient temperature to assure that all components have redissolved. We recommend that source plates be centrifuged to remove any entrapped air bubbles from fhe bottoms of the wells. While manual preparation of source plafes is possible, the use of a robotic dispensing sysfem is highly recommended in order to avoid mistakes in placement of fhe probe inks in fhe wells and to avoid cross-contamination. The use of such a device will also allow more xmiform preparation of subsequent source plates. 

Text excerpted from Robotic Dispensing of Cold Sealants and Adhesives—New Advancements, presented at the 1987 Fall Seminar of The Adhesive and Sealant Council, Inc. 

The first consideration for a miniaturized biosensor array is the size and surface topology of the sensor element. The preparation of biomolecular probes on the surface of each individual sensor element involves manipulating very small volumes of sample, which is normally achieved by the use of microspotters. Most advanced robotic-based liquid dispensing spotters nowadays have resolutions... 

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