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Risedronic acid

Oral formulations are very poorly absorbed with bioavailability ranging from less than 1-6%. Doses should be taken on an empty stomach to improve absorption. Increasing the dose will lead to gastrointestinal complaints. Of the absorbed dose 20-50% is adsorbed to bone and only very slowly released. Free bisphosphonates are eliminated in the urine with an apparent half-live of about 20 hours. However, the elimination half-life of risedronic acid is more than... [Pg.399]

Acide risedronique Acido risedronico Acidum risedronicum NE 58019 Risedronate Risedronic acid. Calcium regulator, used as a bone resorption inhibitor. Merck Co.Inc Procter Gamble Pharm. Inc. [Pg.543]

Nolvadex Tamoxifen (60) Risedronic acid Risedronic acid (94)... [Pg.1177]

Another synthesis of zoledronic and risedronic acids (450) involving corresponding heterocyclic acetic acids (448), phosphorus trichloride (449) as reagents, and methanesulfonic acid (MSA) as the solvent has been presented by Garadnay and co-workers (Scheme 111). ... [Pg.140]

See other pages where Risedronic acid is mentioned: [Pg.95]    [Pg.543]    [Pg.544]    [Pg.752]    [Pg.752]    [Pg.1075]    [Pg.1075]    [Pg.1174]    [Pg.1177]    [Pg.1388]    [Pg.1391]    [Pg.1340]    [Pg.1342]    [Pg.1345]    [Pg.1384]    [Pg.1386]    [Pg.1389]   
See also in sourсe #XX -- [ Pg.95 ]

See also in sourсe #XX -- [ Pg.387 ]

See also in sourсe #XX -- [ Pg.374 , Pg.376 , Pg.380 , Pg.523 ]

See also in sourсe #XX -- [ Pg.226 ]



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