Rieke manganese

Unlike Mn/AcOH, Rieke manganese efficiently couples aromatic ketones, furnishing good to excellent d,l selectivity (Eq. 3.17). As with Mn/AcOH, dialkyl ketones are not suitable substrates for Rieke Mn-mediated pinacol coupling. 

Benzylmanganese sulfonates. A preparation of the.se reagents is by direct reaction if tosylates and mesylates with Rieke manganese in THF at room temperature. They tsehave similarly to Grignard reagents. 

R MnCI is mild enough that chiral a-acyloxy ketones can be prepared. Such organomanganese halides can be directly made from the halides and Rieke manganese. ... 

As a representative procedure, to a slurry of Rieke manganese (10.0 mmol) in THF (10 ml) under argon was added 1-bromododecane (0.80 mmol) at 0°C,... 

The following is a representative procedure. To a slurry of Rieke manganese ... 

The preparation of 3-thienylmanganese bromide 123 is possible via the direct oxidative addition of Rieke manganese to 3,4-dibromothiophene 116 (Scheme 50)... 

Notably, Rieke manganese is able to take part in oxidative addition even where Rieke zinc or Rieke magnesium is insufficiently reactive [258]. The 3-thienylmanganese bromide intermediate 123 can be coupled effectively with both aryl iodides and aroyl chlorides via palladium catalysis to give the products 124 and 125 in moderate to high yields (Scheme 50, Table 28) [343, 344],... 

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