Rhodotorula pilimanae

Liu, A., Neilands, J. B. Mutational Analysis of Rhodotorulic Acid Synthesis in Rhodotorula pilimanae. Vol. 58, pp. 97-106. 

Rhodoturulic acid Rhodotorula pilimanae Fungus (yeast) ... 

H. H. Reidl, T. A. Grover and J. Y. Takemoto (1989). 31P-NMR evidence for cytoplasmic acidification and phosphate extrusion in syringomycin-treated cells of Rhodotorula pilimana. Biochem. Biophys. Acta., 1010, 325-329. 

Perhaps the earliest triple helicate 48 to be characterized, however, is that formed with rhodotorulic acid 46 (HaL ), the dihydroxamate siderophore produced by the yeast Rhodotorula pilimanae [75,76], Subsequently, a related synthetic iron(III) triple helicate 49 based on diprotic tetradentate 1,2-hydroxypyridinone 47 (H2L ) was synthesized (Scheme 5) and characterized by an X-ray structure analysis. 

Bulky ketones such as diaryl ketones can be also reduced by biocatalysts. For example, a rice plant growth regulator, (S )-N-isonicotinoyl-2-amino-5-chlorobenzhy-drol, was prepared by microbial reduction of 2-amino-5-chlorobenzophenone with Rhodosporidium toruloides followed by isonicotinoylation as shown in Fig. 15-42(a)1243). A phosphodiesterase 4 inhibitor was also prepared by microbial reduction of a diaryl ketone 9 with Rhodotorula pilimanae, which was found by the screening of 310 microbial strains [Fig. 15-42(b)][244. ... 

Esterase Origin Rhodotorula pilimanae JUlich Enzyme Products Esterase EL5... 

An iron(III)-binding compound with the properties of a secondary hydroxamic acid has been isolated from supernatant solutions of iron-deficient cultures of a red yeast, Rhodotorula pilimanae (Atkin and Neilands, 1968). The compound rhodotorulic acid (CXVIII) was characterized as LL-3,6-bis (JV-acetyl-3-hydroxyaminopropyl)-2, 5-piperazinedione, i.e., the diketopiperazine of -JV-acetyl-L-5-N-hydroxyomithine. The latter is an amino acid which is a constituent of ferrichromes, albomycins, and fusarinines. In the characterization of rhodotorulic acid, IR, UV, NMR, ORD, and mass spectroscopy were applied. 

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