Rhesus monkeys, reproductive/developmental

Laughlin NK, Bowman RE, Levin ED, et al. 1983. Neurobehavioral consequences of early exposure to lead in Rhesus monkeys Effects on cognitive behaviors. In Clarkson TW, Nordberg GF, Sager PR, eds. Reproductive and developmental toxicity of metals. New York, NY Plenum Press, 497-515. 

During the out-of-season periods, reproductive hormone secretion and gonadal activity are at a complete halt. Although the basic reproductive and developmental physiology appear similar to human in the rhesus monkey and many endpoint parameters are established, the distinct reproductive seasonality requires special timing and has practical implications for widespread use of this model for DART studies. With regard to immune system evaluation it can be assumed that most of the available tests for cynomolgus monkey will also be applicable to rhesus monkeys. 

---