Reversible addition-fragmentation chain transfer polymerisation

Mertoglu M, Gamier S, Laschewsky A, Skrabania K, Storsberg J. Stimuli responsive amphiphilic block copolymers for aqueous media synthesised via reversible addition fragmentation chain transfer polymerisation (RAFT). Polymer 2005 46(18) 7726-40. 

Reversible addition-fragmentation chain transfer polymerisation Arginine-glycine-aspartic acid Room temperature... 

Reversible Addition-fragmentation Chain Transfer Polymerisation... 

Reversible addition-fragmentation chain transfer polymerisation of the highly hydrated zwitterionic poly(2-(methacryloyloxy)ethylphosphoryl-choline (PMPC) block with 2-hydroxypropyl methacrylate (HPMA) in water at 70 °C produced a hydrophobic poly(2-hydroxypropyl methacrylate) (PHPMA) block (38), which drove in situ self-assembly to form well-defined diblock copolymer spheres, worms or vesicles. 

A corresponding principle applies to controlled radical polymerisation performed in quite a number of modes such as nitroxide-mediated polymerisation (NMP), atom transfer radical polymerisation (ATRP), reversible addition fragmentation chain transfer (RAFT) or catalytic chain transfer (CCT) reactions. All of these variants of controlled radical polymerisation lead to well-defined architectures with the particular advantage that a much larger number of monomers are suitable and the reaction conditions are much less demanding than those of living ionic polymerisation reactions. 

LU 05] LuL., YangN., Cai Y., Well-controlled reversible addition-fragmentation chain transfer radical polymerisation under ultraviolet radiation at ambient... 

Baussard J-F, Habib-Jiwanb J-L, Laschewskya A, Mertogluc M, Storsberg, J. New chain transfer agents for Reversible Addition-Fragmentation Chain Transfer (RAFT) polymerisation in aqueous solution. Polymer 2004 45 3615-3626. 

Functionalised PO as block and graft copolymers used as compatibilisers or to increase interactions with other materials are prepared by free radical grafting (the simplest method), metallocene-catalysed copolymerisation of olefins with functional monomers, or anionic polymerisation (silane-containing PO). They are also produced by controlled/living polymerisation techniques such as nitroxide-mediated controlled radical polymerisation, atom transfer radical polymerisation (ATRP), and reversible addition-fragmentation chain transfer (RAFT). 

Quinn JF, Bamer L, Davis TP, Thang SH, Rizzardo E Living free radical polymerisation under a constant source of gamma Radiation—an example of reversible addition-fragmentation chain transfer or reversible termination Macromol Rapid Commun 23 717-721, 2002. 

Functionalised antimicrobial polymers can be developed by chain transfer (reversible addition-fragmentation transfer) polymerisation involving amino derivatives of methacrylate containing polydimethylsiloxane, which are further quarternised to yield new cationic polymers and are useful as antimicrobial coatings. 

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