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Reverse metabolic engineering

Within the diastereomeric switch sequences, the corresponding trans-diols become accessible either using a Mitsunobu inversion or a reversible Diels-Alder cyclization as key reaction step [249,250]. This synthetic strategy is complementary to an approach involving metabolic engineering of E. coli via the chorismate/ isochorismate pathway [251]. [Pg.260]

Koza, J.R., Mydlowec, W., Lanza, G., Yu, J. and Keane, M.A., 2000, Reverse Engineering and Automatic Synthesis of Metabolic Pathways from Observed Data Using Genetic Programming, SMI-2000-0851. [Pg.706]

Csete ME, Doyle JC (2002) Reverse engineering of biological complexity. Science 295 1664-1669 De Figueiredo LF, Podhorski A, Rubio A, Kaleta C, Beasley JE, Schuster S, Planes EJ (2009) Computing the shortest elementary flux modes in genome-scale metabolic networks. Bioinformatics 25 3158-3165... [Pg.153]


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See also in sourсe #XX -- [ Pg.55 ]

See also in sourсe #XX -- [ Pg.55 ]




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Metabolic engineering

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