Retothelial nodule

Non-specific toxic liver damage may be evident in this connection, possible tuberculostatic toxic effects must also be considered. With severe courses of tuberculosis, peliosis hepatis is often observed. Frequently, retothelial nodules are detectable, as demonstrated for the first time in tuberculosis patients by H. Hamperl in 1953. (50) In the course of chronic pulmonary tuberculosis,infiltration of liver cells was noted, as reported in several publications. (50) It was attributed to toxic effects and/or undernourishment or malnutrition. Secondary hepatic amyloidosis, developing in the course of chronic lung tuberculosis, has also been postulated. (50) A restriction of hepatic function in chronic tuberculosis, which was first observed by E. Leuret et al. in 1922, has been described in a number of publications. (51, 60, 63) Depending on the severity and duration of the disease as well as the tuberculostatic pretreatment, we found pathological laboratory parameters in 15-20% and 25-40% of cases respectively. (50)... 

In children and adults, signs of non-specific reactive hepatitis have also been observed. (42, 47) Acidophilic liver cell necrosis occasionally develops, depending on the type of red corpuscles. The endothelial cells are distended, the portal zones show inflammatory infiltration and granulomas or retothelial nodules are frequently found, (s. fig. 25.4) The pathogens can be demonstrated in the liver. Cirrhosis may develop, especially after the destruction of the lobular architecture as a sequela of extensive parenchymal necrosis. There are various serological tests available, including the Sabin-Feldmann... 

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