Retinochoroiditis toxoplasmic

In toxoplasmic retinochoroiditis, serologic tests are used to confirm past exposure to T. gondii by demonstration of specific antibodies, although they cannot confirm a diagnosis, because antibodies can persist for years after acute infection. Enzyme-liked immunosorbent assays... 

It should be noted that a recent, evidence-based, systematic review of published randomized clinical trials of therapy for toxoplasmic retinochoroiditis fitund only three studies that met the authors criteria for inclusion, two of which were carried out more than 35 years ago. Based on this evaluation the authors concluded that there was a lack of evidence to support routine antibiotic treatment for ocular toxoplasmosis, finding no evidence for a beneficial effect on the duration and severity of signs of the disease process. However, the preponderance of evidence supports the concept that appropriate antibiotic therapy is a community standard of care, which is bolstered by guidelines for treatment in many published sources, plus the responses of those practitioners recently surveyed about their preferred patterns of management of the condition. 

SUveira C, Belfort R Jr, Muccioli C, et al.The effect of long-term intermittent trimethoprim/sulfamethoxazole on recurrences of toxoplasmic retinochoroiditis. Am J Ophthalmol 2002 134 41. 

Stanford MR, See SE, Jones LV, et al. Antibiotics for toxoplasmic retinochoroiditis. An evidence-based systematic review. Ophthalmology 2003 110 926. 

Ben Zina Z, Abid D, Kharrat W, Chaker N, Aloulou K, Chaabouni M. Interet du traitement par clindamycine en sous conjonctivale dans les retinochoroidites toxoplasmi-ques. [Interest in treatment with subconjunctival clindamycin in toxoplasmic retinochoroiditis.j Tunis Med 2001 79(3) 157-60. 

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