Restenosis dipyridamole

Schwartz et al. (29) examined the role of antiplatelet therapy in preventing restenosis following balloon angioplasty. They randomized 376 patients to receive either aspirin plus dipyridamole or placebo (similar to previous bypass studies). The active treatment arm received aspirin (330 mg) and dipyridamole (75 mg) three times daily for 24 hours prior to the procedure eight hours before PTCA, the oral dipyridamole was replaced with intravenous dipyridamole (10 mg/hour for 24 hours)—the oral aspirin was continued ... 

Schwartz L, Bourassa MG, Lesperance J, et al. Aspirin and dipyridamole in the prevention of restenosis after percutaneous transluminal coronary angioplasty. N Engl J Med 1988 318 1714-1719. 

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