Rescue therapy

Landman R, Descamps D, Peytavin G, Trylesinski A, Katlama C, Girard PM, Bonnet B, Yeni P, Bentata M, Michelet C, Benalycherif A, Brun VF, Miller MD, Flandre P (2005) Early virologic failure and rescue therapy of tenofovir, abacavir, and lamivudine for initial treatment of HlV-1 infection TONUS study, HIV Clin Trials 6 291-301... 

Albuterol should be used as rescue therapy for patients treated with... 

Gisbert JP, Calvet X, Bujanda L, Marcos S, Gisbert JL, Pajares JM Rescue therapy with rifabutin after multiple Helicobacter pylori treatment failures. Helicobacter 2003 8 90-94. 

Perri F, Festa V, Clemente R, Quitadamo M, Andriulli A Rifabutin-based rescue therapy for Helicobacter pylori infected patients after failure of standard regimens. Aliment Pharmacol Ther 2000 14 311—316. 

Sumatriptan, zolmitriptan, naratriptan, rizatriptan, almotriptan, fro-vatriptan, and eletriptan are appropriate first-line therapies for patients with moderate to severe migraine or as rescue therapy when nonspecific medications are ineffective. 

Corticosteroids may be an effective rescue therapy for status migrainosus, which is a severe migraine that may last up to 1 week. 

Acute bronchospasm Ipratropium HFA inhalation aerosol is not indicated for the initial treatment of acute episodes of bronchospasm where rescue therapy is required for rapid response. 

Beta-2 agonists are still used frequently as the primary method of symptomatically treating asthma attacks. Many patients, for example, inhale beta-2 agonists through MDIs as rescue therapy at the onset of a bronchospastic attack this technique is a mainstay in managing acute episodes of asthma.22,49 Nonetheless, the use of beta-2 agonists as long-term maintenance... 

When an overdose is suspected, immediate hospitalization is recommended. If rescue therapy is delayed, incorrectly administered, or is not available, the result may be anoxic injury (lack of oxygen to the brain, which can cause brain damage) or death. 

DACS SC Stem cell enrichment device Dendreon 9/1999 Rescue therapy following high-dose chemotherapy NA... 

Schmidt RH, Lenz T, Grone HJ, Geiger H, Scheuermann EH. Haemolytic-uraemic syndrome after tacrohmus rescue therapy for cortisone-resistant rejection. Nephrol Dial Transplant I999 14(4) 979-83. 

The fifth tetrahydrofolate compound is 5-formyl THF (folinicacid, citrovorum factor). This compound is not a coenzyme, but it can be converted to any of the active coenzyme forms. It is administered after treatment with the dihydrofolate reductase inhibitor, methotrexate (F ig. 8.47), as a form of rescue therapy. Because it already is in the reduced tetrahydrofolate form, it does not need dihydrofolate reductase to become an active coenzyme. 

Corticosteroids may be an effective rescue therapy for status migrain-osus (a severe, continuous migraine that may last up to 1 week). Open-label studies also suggest that short courses of orally or parenterally administered prednisone, dexamethasone, and hydrocortisone appear to be useful in the management of refractory headache that has persisted for several days. " ... 

When compared with the standard formulation, the microemulsion formulation has demonstrated equivalent or superior efficacy in kidney, liver, and heart transplant recipients. Other areas of research include CSA as monotherapy and as rescue therapy for patients who are unable to tolerate tacrolimus. 

Patients who are unable to tolerate tacrolimus owing to side effects can be switched to CSA as rescue therapy. CSA rescue therapy was studied in a group of kidney and fiver transplant recipients who were unable to tolerate tacrolimus. The initial dose of CSA was based on organ function, tacrolimus levels, and the reason for tacrolimus intolerance and generally began 24 hours after tacrolimus was discontinued. Symptoms improved or resolved in more than 70% of patients within 3 months of conversion to CSA. However, 27% of patients who were switched to CSA experienced an episode of acute rejection. Jain and coUeagues reported similar results with a 39% rejection rate but noted that many patients were able to be converted back to tacrolimus without recurrence of the original complication. 

Abouljoud MS, Kumar A, Brayman KL, et al. Neoral rescue therapy in transplant patients with intolerance to tacrohmus. Clin Transplant 2002 16 168-172. 

Ankersmit HJ, Roth G, Zuckermann A, et al. Rapamycin as rescue therapy in a patient supported by biventricular assist device to heart transplantation with consecutive ongoing rejection. Am J Transplant 2003 3 231-234. 

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