Renal physiology acid-base disorders

Power D A, Duggan J, Brady H R 1999 Renal-dose (low-dose) dopamine for the treatment of sepsis-related and other forms of acute renal failure ineffective and probably dangerous. Clinical and Experimental Pharmacology and Physiology 26(suppl) S23-S28 Rose B D 1989 In Rose B D (ed) Clinical physiology of acid-base and electrolyte disorders, 3rd edn. McGraw Hill, New York, pp. 389-415... 

Disorders of acid-base physiology which are not of respiratory origin are called metabolic disorders. This nomenclature derives from the fact that such disorders result from abnormal metabolism. Metabolic disorders of metabolism may also be due to excessive intake of acid or alkali or to failure of renal function, when the tubular mechanisms for formation of acid or alkaline urine are impaired. 

Mixed disorder of acid-base pbysioiogy This expression is used with two different meanings. Some authors use it to indicate the co-existence of two primary abnormalities, e.g. respiratory acidosis and metabolic acidosis. Others use it as a synonym for compensated , when a primary disorder is accompanied by a super-added physiological response, e.g. compensated respiratory acidosis, when the primary disorder is acidosis and the renal compensation adds a physiological metabolic alkalosis. 

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