Renal handling

Howden, C. W., Reid, J. L., Omeprazole, a gastric proton pump inhibitor lack of effect on renal handling of electrolyte and urinary acidification, Eur. J. Clin. Pharmacol. 1984, 26, 639-640. [Pg.546]

Table IV. Renal Handling of Calcium as Affected by Calcium and Orthophosphates...

K. Hanada, K. Ninomiya, H. Ogata, Pharmacokinetics and Toxicodynamics of Cisplatin and Its Metabolites in Rats Relationship between Renal Handling and Nephrotoxicity of Cisplatin , J. Pharm. Pharmacol. 2000, 52, 1345 - 1353. [Pg.763]

Grantham JJ and Chonko AM. Renal handling of organic anions and cations Excretion of uric acid. In Brenner BM and Rector FC (eds.).7 The Kidney (4th ed). Philadelphia Saunders, 1991. [Pg.47]

Renal handling of uric acid. Uric acid may be actively reabsorbed from the ultrafiltrate following its glomerular filtration or it may be secreted from the blood across the basolateral membrane into the proximal tubular cell. Both passive and active transport mechanisms are involved in the handling of urate. Uricosuric drugs at appropriate doses interfere with these processes. [Pg.444]

Biological issues (i) Mg bioavailabihty, metabolism and physiology . (ii) Cell proliferation and differentiation , (iii) Animal husbandry. (iv) Magnesium in blood . (v) Genetic regulation , (vi) Mineral phase composition of bone and teeth . (vii) Brain and nervous system , (viii) Renal handling of magnesium . [Pg.268]

Oakley PW, Dawson AH, Whyte IM. Lithium thyroid effects and altered renal handling. J Toxicol Chn Toxicol 2000 38(3) 333-7. [Pg.676]

Nagai J, Takano M. Molecular aspects of renal handling of aminoglycosides and strategies for preventing the nephrotoxicity. Drug Metab Pharmacokinet. 2004 19 159-170. [Pg.520]

Mahieu S, Calvo ML. 1998. Effect of chronic poisoning with aluminum on the renal handling of phosphate in the rat. Toxicol Lett 94 47-56. [Pg.333]

Crugten J, Bochner F, Real J, et al. Selectivity of the cimetidine-induced alterations in the renal handling of organic substrates in humans. Studies with anionic, cationic and zwitterionic drugs. J Pharmacol Exp Ther. 1986 236 481-7. [Pg.204]

Tarako et al. (1991) evaluated oxygen supply and energy state in the isolated perfused rat kidney. Metabolic activities of the isolated perfused rat kidney were described by Nishiitsutsuji-Uwo et al. (1967). Cox et al. (1990) used the isolated perfused rat kidney as a tool in the investigation of renal handling and effects of nonsteroidal anti-inflammatory drugs. [Pg.103]

Sarkar SK, Rycyna RE, Lenkinski RE et al. (1991) Yb-DTPA, a novel contrast agent in magnetic resonance imaging application to rat kidney. Magn Reson Med 17(2)328-334 Tenstad O, Roals AB, Grubb A, Aukland K (1996) Renal handling of radiolabeled cystatin C in the rat. Scand J Clin Lab Invest 56 409 114... [Pg.110]

Fanelli GM (1976) Drugs affecting the renal handling of uric acid. In Martinez-Maldonado M (ed) Methods in Pharmacology. Vol 4A Renal Pharmacology. Chapter 9. Plenum Press, New York, London, pp 269-292 Friedman M, Byers SO (1948) Observations concerning the causes of the excess excretion of uric acid in the Dalmatian dog. J Biol Chem 175 727-735... [Pg.115]

The kidneys not only secrete hydrogen ions but they also regenerate bicarbonate ions. The renal handling of electrolytes also influences acid-base balance. [Pg.367]

OH)2D3 concentrations. Low l,25-(OH)2D3 results in little to no intestinal calcium absorption for soft tissue needs. Thus, blood calcium can be low and secondary hyperparathyroidism develops. The inability to regulate renal handling of phosphate by PTH leads to phosphate-mediated repression of ionized calcium. Serious osteodystrophic lesions occur because of high PTH activity on bone resorption resulting in osteitis fibrosa and osteosclerosis. [Pg.34]

Vasopressin, also called antidiuretic hormone (ADH), is a cyclic nonapeptide hormone, which is released from the posterior pituitary. Its primary function in the body is to regulate extracellular fluid volume by affecting renal handling of water. Specific actions include inhibition of... [Pg.336]

Davison JM, Hytten FE. The effect of pregnancy on the renal handling of glucose. J Obstet Gynaecol Br Commonw 1975 82 374-81. [Pg.354]

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