Relative Reactivities of Several Aromatic Compounds

Relative activating ability of aromatic substituents Crystallization 

In this experiment, you will study the bromination of acetanilide, aniline, and anisole  

The classical method of brominating an aromatic compound is to use Br2 and a catalyst such as FeBrg, which acts as a Lewis acid. The first step is the reaction between bromine and the Lewis acid  

The positive bromine ion then reacts with the benzene ring in an aromatic electrophilic substitution reaction  

Aromatic compounds that contain activating groups can be brominated without the use of the Lewis add catalyst because the ir electrons in the benzene ring are more available and polarize the bromine molecule suffidently to produce the required electrophile Br+. This is illustrated by the first step in the reaction between anisole and bromine  

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EXPERIMENT 40 Relative Reactivities of Several Aromatic Compounds 357... 

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