Reissert compounds open-chain analogs

Several open-chain analogs of Reissert compounds have been prepared as part of the study of the mechanism of the acid-catalyzed h3 drolysis of Reissert compounds. A-Benzoyl-A-phenylglycinonitrile (49) has been prepared from glycolonitrile. Although the infrared and... 

Trisubstituted pynoles are obtained in 50-l(X)% yields by the addition of open chain analogs of a Reissert compound to the vinyltriphenylphosphonium cation, with subsequent cyclization by an intramolecular Wittig reaction and base-cataly elimination of HCN (Scheme 25). ... 

A Reissert compound has been prepared from 9-methoxyellipticine and both it and 10 give a fluoroborate salt of the type 19. The Reissert compound of 6,7-dimethoxyphthalazine has been used to prepare an azapa-paverine. The oxoaporphine alkaloid subsessiline has been synthesized using the Reissert compound of 5,6,7-trimethoxyisoquinoline. The reaction of vanillin Schiff bases with benzoyl cyanide yields open-chain analogs of Reissert compounds. a-Acylaminonitriles, which can be considered as open-chain Reissert compounds, have been converted to open-chain analogs of Reissert salts (5-imino-3,5-dihydrooxazole derivatives). - ... 

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See also in sourсe #XX -- [ , ]

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