Regulation of spermatogenesis sertoli-neuroendocrine axis

Sertoli cells are epithelial cells that line the seminiferous tubules of the testes. At their basal aspects, these cells form the basement membrane and tight junctions that make up the highly selective blood-testes barrier, which normally prevents entry of immune cells into the lumen. 

FSH secretion by the anterior pituitary is held in check by negative feedback from the testes. This feedback is 

Testosterone biosynthetic pathways, (a) A Pathway (preferred pathway in human testes), (b) A Pathway (all enzymes located in the endoplasmic reticulum). Enzymes 1,3/i-hydroxy.steroid dehydrogena.se and A-, A -i,somera.se 2, I7a-hydroxylase (CYP 17) 3, Ci7.2o-lyase 4, 17/3-hydroxysteroid dehydrogena.se. 

Regulation of Testicular Steroidogenesis Leydig-Neuroendocrine Axis 

Leydig cells (interstitial cells) are situated in the vascularized compartments outside the seminiferous tubules 

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