Regeneration Ornithine decarboxylase

Aminopropylation The transfer of decarboxylated SAMe is crucial to the synthesis of polyamines (spermine, spermidine, putresdne). Together with ornithine decarboxylase, SAMe determines the synthesis rate of polyamines, which are essential for cell regeneration. At 30 — 60 minutes, the half-fife of SAMe decarboxylase is very short and thus readily adaptable to various metabolic situations. 

RIO. Russell, D. H., and Snyder, S. J., Amine synthesis in regenerating rat liver Extremely rapid turnover of ornithine decarboxylase. Mol. Pharmacol. 5, 253 (1969). 

Poso, A. R., and Poso, H., 1980, Inhibition of ornithine decarboxylase in regenerating rat liver by acute ethanol treatment, Biochim. Biophys. Acta 606 338. 

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