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Recombinant therapeutic glycoprotein

Mokrzycki-Issartel N, Bouchon B, Farrer S, et al. A transient tobacco expression system coupled to MALDI-TOF-MS allows validation of the impact of differential targeting on stmcture and activity of a recombinant therapeutic glycoprotein produced in plants. FEBS Lett., 2003 552(2/3) 170-176. [Pg.882]

K. -S. Jang, Y. -G. Kim, G. -C. Gil, S. -H. Park, and B. -G. Kim, Mass spectrometric quantification of neutral and sialylated N-glycans fiom a recombinant therapeutic glycoprotein produced in the two Chinese hamster ovary cell lines. Anal. Biochem., 386 (2009) 228-236. [Pg.206]

Ghaderi D, Taylor RE, Padler-Karavani V, Diaz S, Varki A. Implications of the presence of N-glycolylneuraminic add in recombinant therapeutic glycoproteins. Nature Biotech 2010 28 863-7. [Pg.202]

Glycosylation is a common and complex posttranslational modification of recombinant therapeutic glycoproteins expressed in eukaryotic expressions... [Pg.294]

In addition to using MOE to improve the presentation of the normal sugars on glycoproteins, such as the human Neu5Ac form of sialic acid derived from ManNAc feeding, this methodology can be extended to control the type of sialic acid added to recombinant therapeutics. For example, Viswanathan and co-workers showed that mannose-6-phosphate, used in place of ManNAc, allowed their glycoengineered insect cells to produce the 2-keto-... [Pg.209]

Raju TS, Briggs JB, Borge SM, Jones AJ (2000), Species-specific variation in glycosylation of IgG evidence for the species-specific sialylation and branch-specific galactosylation and importance for engineering recombinant glycoprotein therapeutics, Glycobiology 10 477-486. [Pg.145]

See other pages where Recombinant therapeutic glycoprotein is mentioned: [Pg.242]    [Pg.1874]    [Pg.194]    [Pg.2134]    [Pg.242]    [Pg.1874]    [Pg.194]    [Pg.2134]    [Pg.207]    [Pg.111]    [Pg.137]    [Pg.405]    [Pg.688]    [Pg.1878]    [Pg.155]    [Pg.237]    [Pg.762]    [Pg.1021]    [Pg.276]    [Pg.2146]    [Pg.406]    [Pg.526]    [Pg.194]    [Pg.205]    [Pg.251]    [Pg.268]    [Pg.104]    [Pg.343]    [Pg.89]    [Pg.231]    [Pg.197]    [Pg.218]    [Pg.406]    [Pg.329]    [Pg.227]    [Pg.861]    [Pg.68]    [Pg.1877]    [Pg.114]    [Pg.155]    [Pg.158]    [Pg.184]    [Pg.186]    [Pg.189]    [Pg.355]    [Pg.20]    [Pg.800]   
See also in sourсe #XX -- [ Pg.1874 ]



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