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Recombinant P450 isoforms

The (p-oxidation of leukotriene (LTB ), an important proinflammatory mediator has been documented in whole animals, isolated cells, and subcellular fractions and shown to be catalyzed by a unique P450 isoform, distinct from those involved in fatty acid and prostanoid metabolism Soon after, the cDNA coding for CYP4F3 was cloned and expressed, and recombinant CYP4F3 shown to catalyze the cp-oxidation of LTB with a of 0.71 p,M A role for... [Pg.534]

In another study by Godin et al. (2007), the rat and human CYP450 isoforms and rat serum esterase that metabolized deltamethrin and esfenvalerate were identified. Table 12 gives the Vmax and kinetic parameters for the metabolism of deltamethrin and esfenvalerate by rat and human recombinant cytochrome P450s. [Pg.64]

See other pages where Recombinant P450 isoforms is mentioned: [Pg.82]    [Pg.82]    [Pg.540]    [Pg.82]    [Pg.82]    [Pg.540]    [Pg.72]    [Pg.48]    [Pg.68]    [Pg.69]    [Pg.536]    [Pg.540]    [Pg.540]    [Pg.541]    [Pg.557]    [Pg.619]    [Pg.201]    [Pg.482]    [Pg.480]    [Pg.119]    [Pg.270]    [Pg.69]    [Pg.73]    [Pg.78]    [Pg.87]    [Pg.228]    [Pg.59]    [Pg.94]   
See also in sourсe #XX -- [ Pg.82 , Pg.86 , Pg.87 ]



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Isoform

Isoforms

Recombinant isoforms

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