Receptors binding constant

Affinity data, like substrate or receptor binding constants, rate constants, like association/dissociation, and Michealis Menten constants, inhibition constants, especially Kj and IC50 values of different enzymes, pharmacokinetic parameters, like absorption rate constants, distribution parameters, clearance, rate constants of metabolic degradation, and elimination rate constants,... 

The low detection limit, high sensitivity, and fast response times of chemoreceptor-based biosensors result primarily from the extremely high binding constants of the receptor R for the target substrate S. The receptor—substrate binding may be described... 

Receptor—substrate-binding constants are typically between 10 and 10, at equimolar ratios, implying that when a receptor—substrate... 

Association constant, the ratio of the rate of onset of a molecule to a receptor binding site and the rate of... 

Table II. Binding Constants for (+)-Anatoxin-a and Related Molecules at Nicotinic and Muscarinic Receptor Sites...

Inhibition constants (Kj) of 26 narcotic analgesic agonists and antagonists as obtained in 4 receptor binding tests (EKC, DHM, DADLE and NAL) [45],... 

The study of receptor-ligand binding is one of the most important applications of free energy simulations [1]. To approach this problem theoretically, one must first partition the conformational space into bound and unbound states. There is no unique way to do this, but in practical situations there is often a natural choice. The equilibrium binding constant is... 

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