Safety matrix reactive chemicals

Experience has shown that reactive chemistry hazards are sometimes undetected during bench scale and pilot plant development of new products and processes. Reactive chemistry hazards must be identified so they can be addressed in the inherent safety review process. Chemists should be encouraged and trained to explore reactive chemistry of "off-normal operations. Simple reactive chemicals screening tools, such as the interactions matrix described in Section 4.2, can be used by R D chemists. 

The Reactive Chemicals Program is an important element in Dow s safety matrix. The research role includes support of the Reactive Chemicals Program, as well as maintaining location reactive chemicals programs within the research organization. The engineer selecting equipment and... 

The reactivity of chemicals used in a process must be assessed, since these chemicals may become in contact in a desired way or accidentally during the process. These interactions are usually analysed in a triangular matrix where the desired and undesired reactions are marked at the intersection of each row and column. Beside chemicals or mixtures, the different fluids (i.e. heat carrier), waste streams, and construction materials must also be considered. An example of such a matrix, summarizing the safety data and the interactions, is represented in Figure 1.3. 

Bioactive paper has recently attracted attention as a new field with applications in global issues such as scarcity of food and water safety [137,138]. The fabrication of inexpensive bioactive packaging, assays, and sensors is urgently required for these issues. Cellulose, the most abundant biopolymer, is a superior candidate for fabrication of bioactive papers because of its biocompatibility and the accumulated knowledge about the material. Cellulose has been used as an ideal support material for bioactive systems, which utilize the pores of the cellulosic matrix to entrap biomolecules [139-143]. The internal surface of pores can be chemically modified, and the functionalized surfaces offer a high selectivity and reactivity for molecular recognition of pathogens. 

---