Reactions not Recognizably Governed by Flux of Ions through Toxin Pores

2 Reactions not Recognizably Governed by Flux of Ions through Toxin Pores 

1 Short Circuiting of G-protein-dependent Signalling Pathways 

This property is characteristic of HlyA and probably extends to other members of the RTX family. The initial interaction of HlyA with the target membrane triggers a G-protein-dependent pathway, and causes generation of diacylglycerol and inositol triphosphate (Grimminger ef al., 1991). HlyA has indeed been identified as the most potent pro- 

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