Reaction with cyanamide

Reaction with cyanamide in the presence of basic catalyst yields thiourea ... 

Bis(triethylstannyl)carbodiimide is similarly obtained from the sodium salt of cyanamide and triethylstannyl chloride. Bis(triphenylstannyl)oxide 8 also undergoes reaction with cyanamide in acetonitrile to give an 88 % yield of bis(triphenylstannyl)carbodiimide 9, mp 98-100 °C.33... 

Under the same conditions reaction with cyanamides affords f,2,3,5-oxathiadiazine-2,2-dioxides (70) in high yield <9lJOU759>. 

Benzo[Z>]thiophen 5-Oxides. - Mild methods for the oxidation of 2,3-dihydrobenzo[Z>] thiophens to the sulphoxide have been developed. The photochemical reactions of various 2- and 3-substituted benzo[ ]-thiophen 1-oxides led to different photodimers. From 3-chlorobenzo[b]-thiophen-2-carboxylic acid 1,1-dioxide, 1,3-oxazinones of biological interest were obtained through cyclization reactions with cyanamides and carbodi-imides. Secondary amines add to 2-phenylbenzo [b] thiophen 1,1-dioxide to give 3-amino-substituted 2,3-dihydro-2-phenylbenzo[b]thiophen 1,1-dioxides. " ... 

Acetamiprid, from Nippon Soda, is obtained in good yields, from trimethyl orthoformate, by sequential reaction with cyanamide and 2-chloro-5-(methylaminomethyl)pyridine (a). [152] Michael Y. Liu and John E. Casida synthesised acetamiprid by alkylation of N-cyano-N-methylacetamidine with 2-chloro-5-(chloromethyl)pyridineinayieldof40% (b). [153]... 

Type J (C—S—C—N—C) Syntheses.—In common with their ir-isoelectronic pyrylium analogues (32), 1,3-oxathiazolium salts (33) are convertible into other ring-systems under the influence of nucleophiles. Their reaction with cyanamide in the presence of sodium ethoxide produces substituted 4-aminothiazoles (36) it probably involves the initial addition of the nitrile moiety at C-2, followed by ring-scission to (35), and recyclization to (36). ... 

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