Reaction rule data base organization

Three rules have been proposed, based on much experimental data, which enable the preferred site of attack to be predicted in a cationic complex which contains more than one organic ligand. It is assumed that the nucleophile seeks out the position of highest positive charge, and that no subsequent rearrangement of the products occurs. That is to say, the reactions are assumed to be under kinetic control. This is not always true while additions of carbanions are often irreversible, phosphines, amines or alkoxides may add reversibly. 

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