Rational library design

Figure 15.1 Cornerstones of rational library design. Modern design strategies require integrative approaches to address many important issues.

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Zheng, W., Cho, S.J., and Tropsha, A. Rational combinatorial library design. 

Teopsha, a., Cho, S.)., Zheng, W. New Tricks for an Old Dog development and application of novel QSAR methods for rational design of combinatorial chemical libraries and database mining. In Rational Drug Design Novel Methodology and Practical Applications, ACS Symposium Series Vol. 719, Paeeill,... 

Cho, S.J., Zheng, W., Teopsha, A. Rational combinatorial library design. 2. Rational design of targeted combinatorial peptide libraries using chemical similarity probe and the inverse QSAR approaches./. Chem. Inf. Comput. Sci. 1998, 38, 259-268. 

Bohm, H.-J. (2001) Progress in structure-based library design. In Rational approaches to drug design Proceedings of the 13th European Symposium on QSAR, Holtje, H.-D. and Sippl, W. (eds.), Prous Science, Barcelona, pp. 367-371. 

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