Rate Equations and Kinetic Models

Kinetic Models toDescribe Drug Degradation inSolution 

When n equals 0, 1, or 2, the reaction is said to be a pseudo-zero-, pseudo-first-, or pseudo-second-order reaction (pseudo-nth-order for higher order reactions), respectively. If the concentration of an additional reactant other than drug D is not constant during the reaction, the reaction order becomes n + 1. 

Simple Pseudo-First-Order Reaction and Zero-Order Reaction 

The differential rate equation for a pseudo-first-order reaction is 

The rate equations for pseudo-zero-order kinetics are 

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Analysis of the rate equation and kinetic model of the conversion of glucose to gluconic acid is discussed in Chapter 11. 

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