Rat organic anion transporter

Sasaki M, Suzuki H, Aoki J, Ito K, Meier PJ and Sugiyama Y. Prediction of in vivo biliary clearance from the in vitro transcellular transport of organic anions across a double-transfected Madin-Darby canine kidney II monolayer expressing both rat organic anion transporting polypeptide 4 and multidrug resistance associated protein 2. Mol Pharmacol 2004 66 450-9. 

T., Endou, H., Sugiyama, Y., Functional characterization of rat organic anion transporter 2 in LLC-... 

Adachi H, Suzuki T, Abe M, Asano N, Mizutamari H, Tanemoto M, Nishio T, Onogawa T, Toyohara T, Kasai S, Satoh E, Suzuki M, Tokui T, Unno M, Shimasagawa T, Matsuno S, Ito S, Abe T. Molecular characterization of human and rat organic anion transporter OATP-D. Am J Physiol Renal Physiol 2003 286 F1188-F1197. 

Hasegawa M, Kusuhara H, Sugiyama D, et al. Functional involvement of rat organic anion transporter 3 (rOat3 Slc22a8) in the renal uptake of organic anions. J Pharmacol Exp Ther 2002 300 746-753. 

Saito H, Masuda S, Inui K. Cloning and functional characterization of a novel rat organic anion transporter mediating basolateral uptake of methotrexate in the kidney. J Biol Chem 1996 271 20719-20725. 

Li N, Hartley DP, Cherrington NJ, et al. Tissue expression, ontogeny, and induci-bility of rat organic anion transporting polypeptide 4. J Pharmacol Exp Ther 2002 301 551-560. 

Mori S, Takanaga H, Ohtsuki S, et al. Rat organic anion transporter 3 (iOAT3) is responsible for brain-to-blood efflux of homovanillic acid at the abluminal membrane of brain capillary endothelial cells. J Cereb Blood Flow Metab 2003 23 432 140. 

Nagata Y, Kusuhara H, Hirono S, et al. Carrier-mediated uptake of H2-receptor antagonists by the rat choroid plexus involvement of rat organic anion transporter 3. Drug Metab Dispos 2004 32 1040-1047. 

Rausch-Derra LC, Hartley DP, Meier PJ, et al. Differential effects of microsomal enzyme-inducing chemicals on the hepatic expression of rat organic anion transporters, OATP1 and OATP2. Hepatology 2001 33 1469-1478. 

Khamdang S, Takeda M, Shimoda M et al. Interactions of human- and rat-organic anion transporters with pravastatin and cimetidine. J Pharmacol Sci 2004 94 197-202. 

Jung KY,Takeda M, Shimoda M, Narikawa S,Tojo A, Kim DK, Chairoungdua A, Choi BK, Kusuhara H, Sugiyama Y, SekineT, and Endou H. Involvement of rat organic anion transporter 3 (rOAT3) in cephaloridine-induced nephrotoxicity in comparison with rOATI. Life Sci 70 1861 -1874, 2002. 

Tokui, T., Nakai, D., Nakagomi, R., Yawo, H., Abe, T., and Sugiyama, Y. (1999) Pravastatin, an HMG-CoA reductase inhibitor, is transported by rat organic anion transporting polypeptide, Oatp2. Pharmaceutical Research, 16, 904—908. 

F., Suzuki, M., Tokui, T, Unno, M., Shimosegawa, T, Matsuno, S., Ito, S., and Abe, T. (2003) Molecular characterization ofhuman and rat organic anion transporter OATP-D. American Journal of Physiology. Renal Physiology, 285, F1188-F1197. 

Guo, G.L. and Klaassen, C.D. (2001) Protein kinase C suppresses rat organic anion transporting polypeptide 1- and 2-mediated uptake. The Journal of Pharmacology and Experimental Therapeutics, 299 (2), 551—557. 

C. D. (2002) Induction profile of rat organic anion transporting polypeptide 2 (oatp2) by prototypical drug-metabolizing enzyme... 

Rost, D., Herrmann, T., Sauer, P., Schmidts, H.L., Stieger, B., Meier, P.J., Stremmel, W., and Stiehl, A. (2003) Regulation of rat organic anion transporters in bile salt-induced cholestatic hepatitis effect of ursodeoxycholate. Hepatology, 38 (1), 187-195. 

Guo, G. L., Staudinger, J., Ogura, K., and Klaassen, C. D. (2002) Induction of rat organic anion transporting polypeptide 2 by pregnenolone-16a-carbonitrile is via interaction with pregnane X receptor. Mol. Pharmacol. 61, 832-839. 

Buist, S.C.N. (2002) Gender-specific and developmental influences on the expression of rat organic anion transporters. J. Pharmacol. Exp. Then 301, 145-151. 

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