Rarity value

This rarity value is equated with the fraction of hits that would be returned by searching large database of diverse molecules with the full pharmacophore (all K features) or thi subset (with K—1 features) as appropriate. Labelling this fraction of hits as p(x) we nov define q x) as the fraction of the M active molecules (i.e. the molecules originally suppliet as input to the procedure) which match each of the K + possible classes. The overal configuration is scored using ... 

What can the library profession do in regard to establishing salvage criteria for the books in research and special libraries—i.e., rarity, value, replaceability, priority for salvage, etc. ... 

While natural and man-made materials can share the same physical and optical properties, there are still considerably differences, the main one being rarity. A natural gem takes considerable time to form and is usually millions of years old. Plus, many feel they have aesthetic quaUties not found in mass-produced materials. While natural and man-made materials appear nearly identical, their values vary considerably. For this reason it is important to be able to distinguish between the two. 

A melting point of 82°-83°C and [ ]D20 —85° - —100° were reported for 2,3-di-O-methyl-D-arabinose by Verheijden and Stoffyn (20). These authors preparation must have been largely or wholly an a-anomer, whereas ours is preponderantly ft. In view of the rarity of crystalline furanoses, it is presumed to be the / -pyranose, and in the PMR spectrum run at 0°C on a sample freshly dissolved in DoO the anomeric proton gave a signal, with the appearance of an unresolved doublet, at t 4.50. This chemical shift and a small value of Jit2, would be expected for H-l of a / -arabinopyranose in the 1C conformation. 

The results of our experiment would indicate that psilocybin (and LSD and mescaline, by analogy) are important tools for the study of the mystical state of consciousness. Experiences previously possible for only a small minority of people, and difficult to study because of their unpredictability and rarity, are now reproducible under suitable conditions. The mystical experience has been called by many names suggestive of areas that are paranormal and not usually considered easily available for investigation (e.g., an experience of transcendence, ecstasy, conversion, or cosmic consciousness) but this is a realm of human experience that should not be rejected as outside the realm of serious scientific study, especially if it can be shown that a practical benefit can result. Our data would suggest that such an overwhelming experience, in which a person existentially encounters basic values such as the... 

Seals Shop. There is a great wealth and variety of seals belonging to the medieval documentation of Spain. Fortunately, these individual pieces of art have survived the ravages of time in a better manner than the documents to which they are appended or applied. Those seals that do require attention are mended with pins and beeswax, but the majority of work done is for exhibitions and to have reproductions available for academic research. Seals of great rarity or historical value are reproduced as they enter the Center, or impressions are made in the field and later cast in this shop. Generally, molds of originals are made of synthetic rubber and casts of resin. One craftsman runs this shop. 

Owing to great similarities in chemical properties and their association together in Natme, the second and third triads of groups 8-10 of the periodic table (Ru, Rh, Pd and Os, Ir, Pt) present many difficulties for the analyst. Their comparative rarity and intrinsic value demand their recovery from spent catalytic converters in the petroleum and many other chemical industries, from the increasing number of pollution control units in motor vehicles, from scrapped jewellery and the scrap of the electronics industry, as well as material from geochemical exploration, the exploitation from mineral deposits, and sweeps . The first requirement is to collect a homogeneous alloy see... 

The medical value of a drug may be independent of the efficacy and rarity of the disease. For example, for Wilson s disease there are several products on the market that are effective and yet additional ones are still being developed. Penicillamine is often effective, but often causes serious adverse reactions. Zinc acetate and trientine are newer products and molybdenum is being evaluated for the same indication. 

Coinage metals Historically, copper, silver, and gold were logical choices for use in coins. These metals are not abimdant in Earth s crust and are considered rare. Most elements occur combined in compounds, but copper, silver, and gold occur nearly pure in rocks fairly close to Earth s surface, making them easy to mine. People revere them because of their beauty and rarity. Finally, their properties allow them to be easily shaped, stamped, and marked for value. 

Specific acid catalysis is also restricted to biologically noncompatible conditions because amides are protonated in oxygen rather than nitrogen with pKa values in the range of <0 [63,64]. The rarity of intermolecular acid/base effects on CTI was affirmed by the kinetic deuterium solvent isotope effects (KSIE) of about 1.0, indicating that the mechanism of spontaneous isomerization does not involve a proton-in-flight [29,42,65]. 

The proportion of fluid elements experiencing a particular anomalous value of the Lyapunov exponent A / A°° decreases in time as exp(—G(X)t). In the infinite-time limit, in agreement with the Os-eledec theorem, they are limited to regions of zero measure that occupy zero volume (or area in two dimensions), but with a complicated geometrical structure of fractal character, to which one can associate a non-integer fractional dimension. Despite their rarity, we will see that the presence of these sets of untypical Lyapunov exponents may have consequences on measurable quantities. Thus we proceed to provide some characterization for their geometry. 

The theory described in section 3.3 is called single channel QDT. It reduces an unperturbed Rydberg series to a small number of constants, which include /z. Were this the only achievement of QDT, it would not have assumed much importance in atomic physics, because most series in the spectra of many-electron atoms are in fact perturbed, so that a constant value of p is a rarity. 

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