Rare Earth Luminescent Chemosensors as Bioimaging Probes

4 Rare Earth Luminescent Chemosensors as Bioimaging Probes 

Zinc (Zn +) is the second most abundant metal ion after iron in the human body, and plays critical roles in regulating gene expression, enzyme regulation, and neurotransmission [90]. Zn + is also known to be responsible for the formation of amyloid plaques during the onset of Alzheimer s disease [91], At present, there is considerable interest in the development of Zn +-selective luminescence chemosensors as bioimaging probes [92, 93], 

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