Rabbit over-marking

Domestic female rabbits mark more when in estrus and prefer to over-mark scent marks by males. They also prefer to mark over chin marks, as opposed to urine and control odors, and prefer to over-mark chin marks from donors living in a long daylight cycle over those from short-day animals (Hudson and Vodermayer, 1992). 

The bone becomes depleted of calcium salts when the urine is acidic over a relatively long period. This was shown by Goto (17) who fed rabbits large doses of hydrochloric acid. He then showed that urinary calcium loss occurred in concert with a marked reduction in mass of the skeletal system, and also that the total non-fat dry weight of bone decreased,implying a loss of bone matrix. A dose-dependent, dietary acid induced loss of labelled calcium from rat bone has been reported by Thorn and his coworkers (18). They demonstrated that in response to graded doses of ascorbic acid, cells in tissue culture, and bones in whole animals fed such doses were depleted of the labelled calcium. 

Papaverine does not cause deep narcosis or marked analgesia. It may produce convulsions, and cause the Straub tail reaction. The excitability of isolated nerves and muscles is abolished. Respiration is not profoundly affected. A single injection in rabbits causes an increase in blood sugar which is cancelled out by adrenalectomy or by a repetition of the injection over a period of days. Hyperglycemia follows withdrawal. 

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