Ra-mer

Rossotti and co-workers45 introduced the term "oligomers for dimers and even multimers or ra-mers in non-aqueous solutions real examples of such self-aggregates (non-hydrogen bonded) have been reported46 for quaternary ammonium thiocyanates, iodides and perchlorates with ra-mers with n even up to 20. 

Ra)mer, M.D., Personal Communication presented to the South Pacific Conmission, 1977. 

Electrospray ionization of polymers was introduced in 1968 (7) in an effort to study polystyrene by ms. In 1984, the technique was further developed for biopolymers (8). Spectra of poly(ethylene glycols) (PEG) up to molecular masses of 17,500 were also obtained using esi (9). In 1992, esi techniques were used to obtain ms on a poly(ethylene oxide) (PEO) of about 5,000,000 (2). Since esi techniques multiply charge macromolecules, both these studies were able to get spectra on a quadrupole ms with an miz of less than 2000, where z is the number of charges. However, with many different ra-mers in a normal narrow MMD of a synthetic pol5mier, the effect of z often as high as 40 means that one needs to obtain resolution in mIz of a small fraction of a mass unit to see the entire MMD. 

Fig. 4. Detail of MALDI-tof-ms of polystyrene pol3rmer shown in Fignre 3. The smaller peaks between the main peaks have been shown (21) to be the result of matrix adducts. This is an example where these intermediate peaks are not from polymer molecules terminated with other end groups or from ra-mers charged with different salts.

Figure 2.61 The methyl region of the H NMR spectrum of mer-RhClj(PMe2Ph)3 demonstrating the virtual coupling of the resonances as a result of the mutually /ra/is-phosphines. (Reproduced with permission from S.A. Cotton and F.A. Hart, The Heavy Transition Elements, published by Macmillan Press Ltd, 1975.)...

Santra S, Liesenfeld B, Bertolino C, Dutta D, Cao Z, Tan WH, Moudgil BM, Mer-icle RA (2006) Fluorescence lifetime measurements to determine the core-shell nanostructure of FlTC-doped silica nanoparticles An optical approach to evaluate nanoparticle photostability. J Luminesc 117 75-82... 

Four spots of DNA probes were applied in a PMMA microchannel (500 pm wide, 50 pm deep). This is intended for detection of low-abundant point mutation in the K-ras gene, which is diagnostic for colorectal cancer. Aminated 24-mer DNA probes were immobilized via glutaraldehyde hnkage on the amine groups... 

Initially, some linear libraries of penta-, hexa-, octa and decamers with structure (A )ra-/J- -/J- -TentaGelS (where ft = /1-alanine and s = e-aminocaproic acid) were tested. For each position 19 natural amino acids (cysteine was avoided) were used, and the active ligand structures are shown in Figure 8.13. Some recurrent motifs emerged, such as FDW and QDPR, especially for 5- and 6-mers, and WXXGF for 8- and 10-mers. 

Phillips JA, Craig SJ, Bayley D, Christian RA, Geary RS, Nicklin PL. Pharmacokinetics, metabolism and elimination of a 20-mer phosphorothioate ohgodeoxynu-cleotide (CGP 69846a) after intravenous and subcutaneous admi n istration. Iliochem Pharmacol 1997 54(6) 657-68. 

Bames D, Huglies RA, Monds RW, Wade-Jones O, Brown P, Britton T, Francis DP, Perkin GD, Rudge P, Swaslr M, Kadifi H, Fai mer S, Frankel J (1997) Randomized trial of oral and inti avenous metlrylprednisolone in acute relapses of multiple sclerosis. Lancet 349 902-906. 

The observation of a single sharp chromatographic peak finr ti otK-to-one addua suggested that it is a sii lc R msomo , ra r than a mixture of the two regioiso-mers which are possible firom the prcqxiscd soccer ball structure for Cm- This would be... 

We wish to report that the g-ketoamine 5-amino-2,2-dimethyl-hex-4-en-3-one (Hadmh) gives soluble Co(III) complexes, Co(admh)3 (1., R = H, Ra = CHg, Ry = C(CHg)g, M = Co), which can be separated into fee- and mer- isomers and can be characterized by a variety of physical methods. The marked increase in solubility is due to introduction of the tert-butyl group. 

Cho, B.P., Beland, F.A., and Marques, M.M. (1994) NMR structural studies of a 15-mer DNA duplex from a ras protooncogene modified with the carcinogen 2-aminofluorene conformational heterogeneity. Biochemistry, 33, 1373-1384. 

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