Quinovic acid derivatives

Table 3. Characteristic chemical shift of key carbons in quinovic acid derivatives.

Carbons Quinovic acid derivatives C-27 glucosylesters of quinovic acid C-28 glucosylesters of quinovic acid... 

Table 7. Antiviral activity of quinovic acid derivatives 15-20 and 25-27 against HRV-IB and VSV infection.

A number of alkaloids producing a pronounced enhancement of phagocytosis were isolated by Wagner et al. (20) As a part of our continuing search for new biologically active metabolites from U. tomentosa we preceded to a bioassay-directed fractionation of the extracts from V. tomentosa. The extracts and fractions have been bioassayed by the carrageenan induced edema test on rat paw. This allowed us to identify a quinovic acid derivative with a C-3,27 glycosidation pattern, 21. as one of the active anti-inflammatory principles of U. tomentosa. (11). 

Phytochemistry The whole plant contains up to 2 % alkaloids, the main ones being zygofabagine, harmine, and others. Leaves contain 15.7-70 mg% and fruits up to 10 mg% of vitamin C (Seredin and Sokolov 1969). The baik contains trite-penoid glycosides, quinovic acid and its derivatives as well as a cinchoUc add derivative (Feng et al. 2007). 

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