Quinolone antibacterials, naming

Carboxylic acid substituted quinolin-4-one derivatives constitute another class of biologically active compounds often known under the collective name quinolones . The development of quinolone antibacterials since the discovery of naphthyridine agent, nalidixic acid, has progressed with periods of great innovation. 

Quinolones is the name given to a broad family of synthetic chemotherapeutic antibacterials chemically based on the 4-quinolone and 1,8-naphthyridine structures. The structures of these two quinolone nuclei and an example of a drug from each of these groups are shown in Fig. 6.17a, b. Cinoxacin is an example of a... 

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