Quantitative structure-activity relationships QSARs for hypoxic cell radiosensitizers

3 Quantitative structure-activity relationships (QSARs) for hypoxic cell radiosensitizers 

There are two caveats to such an argument. Firstly, analysis of the radiosensitization data for different levels of effect showed that the slope of equation (16) varied with effect. This implies two (or more) mechanisms, with different redox dependencies, are involved. Secondly, the experimental 

Although activity in the search for inqiroved hypoxic cell radiosensitizers has decreased, the contribution of radiation chemistry in defining the range of reduction potentials which are needed for effective radiosensitizers was seminal. 

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