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Quadruplex Ligand Recognition Biological Aspects

JEAN-FRANgOIS RIOU, DENNIS GOMEZ, HAMID MORJANI AND CHANTAL TRENTESAUX [Pg.154]

Laboratoire d Onco-Pharmacologie, JE 2428, UFR de Pharmacie, Universite de Reims Champagne Arderme, 51 rue Cognacq-Jay, 51096, Reims, France [Pg.154]

The extreme ends of chromosomes represent a fascinating field of investigation for scientists because of the difference existing between telomeres and the other parts of the chromosome. [Pg.154]

The objective of this chapter is to present the latest view on the cellular mechanism(s) of action of G-quadruplex ligands and to discuss their potential use in therapy. [Pg.154]

The telomeres of human cells range in size from 3 to 15 kb and are comprised of tandem repeats of the sequence (5 -TTAGGG-3 ) with a 3 overhang of the [Pg.154]

See other pages where Quadruplex Ligand Recognition Biological Aspects is mentioned: [Pg.154]    [Pg.155]    [Pg.157]    [Pg.159]    [Pg.161]    [Pg.163]    [Pg.165]    [Pg.167]    [Pg.169]    [Pg.171]    [Pg.173]    [Pg.175]    [Pg.177]    [Pg.179]    [Pg.154]    [Pg.155]    [Pg.157]    [Pg.159]    [Pg.161]    [Pg.163]    [Pg.165]    [Pg.167]    [Pg.169]    [Pg.171]    [Pg.173]    [Pg.175]    [Pg.177]    [Pg.179]   


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