Toxoplasmosis pyrimethamine for

It is used in the treatment of severe anaerobic infections caused by bacteroides and other anaerobes. It is also used in combination with aminoglycoside in the treatment of abdomen and GIT wounds, infections of female genital tract, pelvic abscesses, aspiration pneumonia and septic abortion. It is also used for prophylaxis of endocarditis. It is also used along with primaquine in Pneumocystis carinii pneumonia in AIDS patients and with pyrimethamine for toxoplasmosis. 

Hematological toxicity, including bone marrow suppression (4) and hemolysis (5), has been observed, especially during combined treatment with spiramycin and pyrimethamine for toxoplasmosis. 

Pyrimethamine does not appear to alter zidovudine pharmacokinetics, and zidovudine does not appear to alter the prophylactic efficacy of sulfadoxine/pyrimethamine for toxoplasmosis. The combination of pyrimethamine and zidovudine may increase the risk of myelosuppression. 

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See also in sourсe #XX -- [ ]

See also in sourсe #XX -- [ ]

See also in sourсe #XX -- [ , , ]

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