Pyoverdins and Related Siderophores from Pseudomonas spp

The most thoroughly investigated representatives are the pyoverdins, also spelled pyoverdines and occasionally named pseudobactins 353), produced by the fluorescent members of the genus Pseudomonas. For reviews see 44, 231) for a detailed 

Chart 1. Condensation of a Dab residue with the preceding amino acid residue 

Complete structural analysis requires mass spectral and NMR data as well as chemical degradation and analysis of the chirality of the constituent amino acids, determination of the mode of linkage of lysine (a- or s-), the size of the cyclopeptide or cyclodepsipeptide ring, etc. (37). In some cases sttuctures have been proposed based only on mass spectral data. Difficulties arising in this approach were discussed (44). To determine the three-dimensional structure an X-ray 

Plate 1. X-ray structure (stereo view) of ferri-pyoverdin BIO (ferri-4) 

Plate 2. Calculated three-dimensional structure of the Ga -complex of pyoverdin PL8 (without side chain) Chra-Lys-acetylOHOm-AIa-Gly-aThr-Ser-cOHOm 

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